Biopsies were formalin fixed, paraffin embedded and stained with hematoxylin and eosin. Histopathological examination was possible in 17 patients. All the patients were examined under Wood′s lamp to determine the depth of pigmentation. History of onset, affected family members and triggering factors of POM were noted. One hundred consecutive patients of periorbital melanosis attending the outdoor clinic of Rita Skin Foundation constituted the sample population. This study explores the relationship between POM and PDL-F by clinical and histopathological parameters. Recently two more PDLs have been described in the Indian population. Thus far, six demarcation lines have been described and given names according to the alphabets A to F. Pigmentary demarcation lines (PDL) are sharp demarcation lines present over the different parts of the body. POM has been stated to result from a variety of reasons they include dermal melanin deposition, post inflammatory hyperpigmentation from atopic or contact allergic dermatitis as well as shadowing from lax skin and infraorbital swelling. It is popularly known as "dark circles" and has also been referred to as "infraorbital skin discoloration," "infraorbital darkening" and "some darkening of the skin around the eyes." There has been little investigation as to the cause of this common disorder consequently, varied methods of treatment have been carried out with variable outcomes. Periorbital melanosis (POM) is an ill-defined entity and is a common cosmetic concern. Pigmentary demarcation line-F continued as POM around the eyeįigure 1: Periorbital melanosis, uniform hyperpigmented patch around the eyes
Turning of the face reveals a hyperpigmented patch on the side of the face with a sharp border (PDL-F). Figure 4: Histopathology from POM showing melanophages in the upper dermis (H and E stain, X400)įigure 3: Periorbital melanosis and pigmentary demarcation line over the face in mother and daughterįigure 2: Same patient as in Figure 1.
0 kommentar(er)
